Dr. Sandra D. Michael
SUNY Distinguished Service Professor
BA, California State College at Sonoma
PhD, University of California at Davis
Polycystic ovary disease and ovarian cancerBeginning with the whole animal and ending at the subcellular level, this laboratory uses the female mouse for the study of polycystic ovary disease and ovarian cancer. In our studies, a variety of research methods and techniques are applied, some of which are: neonatal thymectomy, steroid injections, cellular infusions, FACS analyses, immunohisto-chemistry, histology, subcellular fractionation via differential centrifugation, thymic hormone and steroid hormone assays, steroid receptor assays, and steroid- and energy-producing enzyme assays. Ovarian cancer and polycystic ovary disease affect large numbers of women every year. Our research has the potential to shed additional light on these two dreaded diseases, as well as to add to a compendium of information on the overall aspects of female reproduction.